Braden Montgomery hit a two-run homer in the 10th inning of his rousing major league debut to rally the Chicago White Sox past the Atlanta Braves 6-5 on Tuesday night.

Braves star Ronald Acuña Jr. left the game in the fourth inning after suffering an injury running to first base on a ground ball.

The Braves, coming off a three-game sweep of the Pirates last weekend, lost a series opener for the first time since dropping the opener to the Marlins on May 18.

It was also just the second time this season the Braves suffered a walk-off loss. The other such loss came back on April 5 against the Diamondbacks. That game also turned out to be a 6-5 loss in 10 innings.

Miguel Vargas launched a two-run shot in the third to begin Chicago’s comeback from a 4-0 deficit against the Braves, who have the best record in the majors at 45-22. Montgomery made it 4-3 with an RBI single in the fourth, and Jacob Gonzalez tied it with a run-scoring single in the seventh.

The second-place White Sox (35-31) moved within a half-game of scuffling Cleveland atop the AL Central.

Matt Olson homered twice in the first three innings for Atlanta, accounting for three runs. Mauricio Dubón put the Braves up 5-4 in the top of the 10th with an RBI single.

With two outs in the bottom half, Montgomery connected on an 0-1 changeup from closer Raisel Iglesias (0-1) and sent it 343 feet over the left-field wall to send the Rate Field crowd into a frenzy.

Automatic runner Andrew Benintendi scored from third ahead of Montgomery.

Material from The Associated Press was used in this article.

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