DUBAI, United Arab Emirates (AP) — The U.S and Iran traded strikes for a second day, pushing the Middle East closer to the resumption of a full-scale war.

The American attack, which lasted into Thursday morning in Iran, appeared more intense and wider than the day before, but Tehran released little information on the extent of the damage. An Indian official said a U.S. attack on an oil tanker allegedly trying to violate Washington’s blockade on Iranian ports killed three Indian mariners, underscoring the danger to seafarers.

It was the third time this week that back-and-forth strikes have rattled the Middle East. The first involved attacks between Iran and Israel, followed by the two rounds of fire between the U.S. and Iran, which hit countries in the region that host American bases.

The new exchange of fire came as efforts to negotiate an end to the war appeared stuck, with U.S. President Donald Trump warning that Tehran would “pay the price” for stalled negotiations. Iran’s Foreign Ministry said in a statement Thursday that the U.S. attacks had “effectively rendered the ceasefire ... meaningless,” without saying it was abandoning it.

Central to the negotiations is Iran’s stranglehold on the Strait of Hormuz, which has disrupted global energy supplies, driven up fuel prices and made food and other basics more expensive well beyond the region.

Iran announced Thursday that the strait was closed — but it was unclear what that meant since it has severely restricted traffic through the waterway since early in the war and only a trickle of ships have gotten through. The U.S. military's Central Command disputed the claim — and Trump said Wednesday that the U.S. has undertaken a secret mission in recent weeks to sneak ships through the passage.

The two sides also remain at odds over Iran's nuclear program, which Tehran insists is peaceful but which the U.S. and Israel fear could be used to build an atomic weapon due to its stockpile of highly enriched uranium. The U.S. and Israel said a major reason they went to war on Feb. 28 was to ensure that Iran would never be able to do that.

US strikes Iran and Iran fires back at Gulf states

Central Command said its latest round of airstrikes came “in response to Iran’s unwarranted and continued aggression” and targeted “Iranian military surveillance capabilities, communication systems and air defense sites.” It did not elaborate on the damage done by the strikes, which it said ended just before sunrise Thursday in Iran.

Explosions from the strikes echoed around Iran’s capital, as well as the port city of Bandar Abbas and other southern areas along the Strait of Hormuz. Iran's paramilitary Revolutionary Guard later said sites hit included a manufacturing complex, a military barracks and a local Guard base outside of Tehran.

Iran said it fired back at Kuwait, Bahrain and Jordan, as it had a day before.

Kuwait closed its airspace for several hours because of the attack, but did not elaborate on any damage. Jordan said it intercepted 20 Iranian missiles fired toward an area that is home to a base hosting U.S. troops, though no one was hurt.

Bahrain's Interior Ministry said an 11-year-old girl was hurt and cars and homes were damaged by debris from interceptions responding to the Iranian attack.

Meanwhile, Israel warned residents in the country’s north to seek shelter after the detection of suspected incoming fire from Lebanon, where Israel is fighting the Iran-allied Hezbollah militant group.

Trump says the US is sneaking oil through the Strait of Hormuz

Iran's ability to control the Strait of Hormuz has proved a strong bargaining chip since the narrow waterway's effective closure has severely disrupted the global economy.

Trump said Wednesday that the U.S. military has undertaken a mission since last month to sneak oil shipments past Iran’s forces in the strait, aided by the destruction of Iranian radar equipment.

Trump said as a result more than 100 million barrels of oil have evaded Iran’s chokehold. There was no immediate confirmation of that figure, which equals roughly five days of oil shipments through the waterway before the war began.

But the seas remain dangerous for mariners. Indian Ports, Shipping and Waterways Minister Sarbananda Sonowal announced on X that three Indians missing after the American attack on the tanker Settebello had been killed. The U.S. military’s Central Command had accused the Settebello of having “violated the ongoing blockade by attempting to transport oil from Iran.” American forces fired into the ship’s engine room to stop it Wednesday.

The leader of the International Maritime Organization, a United Nations agency, condemned the attack.

Another tanker near where the Settebello was struck off Oman experienced a fire in its engine room on Thursday, according to the British military's United Kingdom Maritime Operations center. It wasn't immediately clear what sparked the blaze.

Big disagreements stand in the way of a quick peace deal

Trump suggested earlier this week that an agreement with Iran could be close — but the exchanges of fire have called that into question, and big differences remain.

The U.S. wants to see Iran give up its stockpile of highly enriched uranium, which is a short technical step from weapons-grade levels.

Iran is refusing to give up the uranium and demanding relief from sanctions. It also wants the release of frozen assets even before a final agreement is in place, something Trump rejected.

Iran has insisted that any deal to end the war must also end fighting between its ally Hezbollah and Israel. But Israeli Prime Minister Benjamin Netanyahu appears intent on pursuing his goal of destroying the militant group.

A Qatari diplomatic delegation, negotiating in coordination with the U.S., left Tehran on Thursday morning after holding talks, according to an official with knowledge of the team who spoke on condition of anonymity to discuss the mediation. Pakistan, meanwhile, expressed deep concern over rising tensions and urged both Iran and the U.S. to adhere to the ceasefire.

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Price and Toropin reported from Washington. Associated Press writers Sheikh Saaliq in New Delhi, Munir Ahmed in Islamabad and Victoria Eastwood in Cairo contributed to this report.

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